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Prednisolone

Catalog No. S1737 Name Selleck Chemicals
CAS Number 50-24-8 Website http://www.selleckchem.com
M. F. C21H28O5 Telephone (877) 796-6397
M. W. 360.44402 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 738

SYNONYMS

IUPAC name
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
IUPAC Traditional name
prednisolone
Synonyms
Decaprednil
Hydroretrocortine
Predonine

DATABASE IDS

CAS Number 50-24-8

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Inflammation
Biological Activity:
Prednisolone(Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. [1,2]

REFERENCES

  • http://en.wikipedia.org/wiki/Prednisolone