2-Methyl-3-butyn-2-ol

• Catalog No.: L07593
• CAS Number: 115-19-5
• M. F.: C5H8O
• M. W.: 84.11642
• Purity: 98%

SYNONYMS

• Title: 2-甲基-3-丁炔-2-醇
• IUPAC name: 2-methylbut-3-yn-2-ol
• IUPAC Traditional name: 2-methyl-3-butyn-2-ol
• Synonyms: 2,2-Dimethylpropargyl alcohol

DATABASE IDS

• MDL Number: MFCD00004467
• CAS Number: 115-19-5
• EC Number: 204-070-5
• Merck Index: 146034
• Beilstein Number: 635746

PROPERTIES

• Purity: 98%
• Boiling Point: 103-104°C
• Density: 0.863
• Flash Point: 22°C(72°F)
• Melting Point: 2-3°C
• Refractive Index: 1.4210
• GHS Hazard statements: H225-H301-H318
• European Hazard Symbols: X
• GHS Precautionary statements: P210-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-22-41
• RTECS: ES0810000
• Safety Statements: 23-26-36/39
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1987
• Packing Group: II

REFERENCES

• Adduct of acetylene and acetone which acts as an acetylene equivalent in the Pd-catalyzed (Sonogashira) coupling reaction with aryl or heteroaryl halides, permitting a one-pot diarylation by different halides: Synthesis, 571 (1984):
  
• Alternatively, the protecting group can be removed from the intermediate by base to give monoarylacetylenes: J. Org. Chem., 48, 5135 (1983); 57, 6998 (1992). For an improved procedure, see: Synthesis, 589 (1996).