Sodium ethoxide

• Catalog No.: L06230
• CAS Number: 141-52-6
• M. F.: C2H5NaO
• M. W.: 68.05027
• Purity: 96%

SYNONYMS

• Title: 乙醇钠
• IUPAC name: sodium ethanolate
• IUPAC Traditional name: sodium ethoxide
• Synonyms: Sodium ethylate

DATABASE IDS

• Beilstein Number: 3593646
• MDL Number: MFCD00012417
• Merck Index: 148613
• EC Number: 205-487-5
• CAS Number: 141-52-6

PROPERTIES

• Purity: 96%
• Flash Point: 30°C(86°F)
• Melting Point: >300°C
• GHS Hazard statements: H251-H314-H318
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• Risk Statements: 11-14-34
• Safety Statements: 8-16-26-43-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 4.2
• UN Number: UN3206
• Packing Group: II

REFERENCES

• In reactions where the presence of excess ethanol is undesirable, the use of pre-formed solid sodium ethoxide is much more convenient and safer than preparation in situ from sodium metal. This applies to many literature condensation reactions which employ powdered sodium in, for example ether or toluene, where the difficulty and hazards of obtaining a satisfactory sodium dispersion can be considerable. Solid sodium ethoxide often gives superior results, with better control of exothermic reactions.
• Extensively used as a base for the generation of carbanions in a variety of alkylation and condensation reactions. Organic Syntheses examples of the use of solid sodium ethoxide include:
• Condensation of acetone with ethyl acetate: Org. Synth. Coll., 3, 17 (1955). Benzoylation of acetophenone with ethyl benzoate: Org. Synth. Coll., 3, 251 (1955). ɑ-Formylations with ethyl formate: Org. Synth. Coll., 3, 300 (1955); 4, 536 (1963). ɑ-Ethoxalylation of diethyl succinate with diethyl oxalate: Org. Synth. Coll., 5, 687 (1973).