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Praziquantel

Catalog No. S1691 Name Selleck Chemicals
CAS Number 55268-74-1 Website http://www.selleckchem.com
M. F. C19H24N2O2 Telephone (877) 796-6397
M. W. 312.40606 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 929

SYNONYMS

IUPAC name
2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one
IUPAC Traditional name
praziquantel
Synonyms
Droncit
Biltricide

DATABASE IDS

CAS Number 55268-74-1

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Praziquantel(Biltricide, Droncit) is an anthelmintic effective against flatworms. It increases the permeability of the membranes of schistosome cells towards calcium ions. The drug, thereby induces contraction of the parasites, resulting in paralysis in the contracted state. The dying parasites are dislodged from their site of action in the host organism and may enter systemic circulation or may be destroyed by host immune reaction (phagocytosis). Additional mechanisms including focal disintegrations and disturbances of oviposition (laying of eggs) are seen in other types of sensitive parasites. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Praziquantel