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Ipratropium bromide_Molecular_structure_CAS_22254-24-6)
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Ipratropium bromide

Catalog No. S1683 Name Selleck Chemicals
CAS Number 22254-24-6 Website http://www.selleckchem.com
M. F. C20H30BrNO3 Telephone (877) 796-6397
M. W. 412.3611 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72782

SYNONYMS

IUPAC name
(3R)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azabicyclo[3.2.1]octan-8-ium bromide
IUPAC Traditional name
(3R)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-isopropyl-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide
Synonyms
Apovent
Atrovent
Aerovent

DATABASE IDS

CAS Number 22254-24-6

PROPERTIES

Salt Data Bromide
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Ipratropium bromide is a muscarinic antagonist, bronchodilator, N-Isopropyl salt of atropine. In anaesthetised guinea-pigs, bronchoconstriction induced by vagal nerve stimulation was potentiated by low doses of the antimuscarinic bronchodilator drug, ipratropium (0.01-1.0 µg/kg); the maximum effect was obtained with 1.0 µg/kg which doubled the bronchoconstriction. When the dose was increased above 1.0 µg/kg potentiation no longer occurred; instead the vagally induced bronchoconstriction was antagonised. [1]

REFERENCES

  • http://www.ncbi.nlm.nih.gov/pubmed/2958300