Chloramphenicol

• Catalog No.: S1677
• CAS Number: 56-75-7
• M. F.: C11H12Cl2N2O5
• M. W.: 323.12938
• Storage: -20°C

SYNONYMS

• IUPAC name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• IUPAC Traditional name: chloromycetin
• Synonyms: Chlornitromycin; Alficetyn; Chloromycetin

DATABASE IDS

• CAS Number: 56-75-7

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Chloramphenicol(Chloromycetin) is a bacteriostatic antimicrobial. It is considered as a prototypical broad-spectrum antibiotic. It is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most of anaerobic organisms. It is bacteriostatic (that is, it stops bacterial growth). It is a protein synthesis inhibitor, inhibiting peptidyl transferase activity of the bacterial ribosome, binding to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit, preventing peptide bond formation. [1]

REFERENCES

• http://en.wikipedia.org/wiki/Chloramphenicol