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Zolmitriptan

Catalog No. S1649 Name Selleck Chemicals
CAS Number 139264-17-8 Website http://www.selleckchem.com
M. F. C16H21N3O2 Telephone (877) 796-6397
M. W. 287.35684 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72776

SYNONYMS

IUPAC name
(4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
IUPAC Traditional name
zomig
Synonyms
Zomig
AscoTopand
Zomigon
Zomigoro

DATABASE IDS

CAS Number 139264-17-8

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Zolmitriptan(Zomig) is a selective serotonin receptor agonist. It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches. Cytochrome 1A2 is likely to be the isoenzyme responsible for the metabolism of zolmitriptan. The increased exposure to zolmitriptan and 183C91 by cimetidine indicated that a reduction in the total daily recommended dose of zolmitriptan may be necessary when treating migraine patients who are taking nonspecific cytochrome P450 inhibitors or specific cytochrome 1A2 inhibitors. [1][2]

REFERENCES

  • http://en.wikipedia.org/wiki/Zolmitriptan