5-Aminouracil

• Catalog No.: L04452
• CAS Number: 932-52-5
• M. F.: C4H5N3O2
• M. W.: 127.1014
• Purity: 97%

SYNONYMS

• Title: 5-氨基脲嘧啶
• IUPAC name: 5-amino-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 5-amino-1,3-dihydropyrimidine-2,4-dione
• Synonyms: 5-Amino-2,4-dihydroxypyrimidine

DATABASE IDS

• Beilstein Number: 127250
• MDL Number: MFCD00006025
• EC Number: 213-252-3
• CAS Number: 932-52-5

PROPERTIES

• Purity: 97%
• Melting Point: >300°C
• GHS Hazard statements: H301
• European Hazard Symbols: X
• GHS Precautionary statements: P264-P270-P301+P310-P321-P405-P501A
• Risk Statements: 22
• RTECS: YQ8740000
• Safety Statements: 36
• TSCA Listed: 是

REFERENCES

• Condensation with crotonaldehyde gives 2,4-dioxo-6-methylpyrido[3,2-d]pyrimidine: J. Chem. Soc. (C), 1745 (1967). An improved procedure has been used in synthesis of inhibitors of human thymidylate synthase: J. Med. Chem., 27, 1710 (1984), and of dihydrofolate reductases: J. Med. Chem., 39, 1836 (1996):
  
• Review of the use of uracils as starting materials in heterocyclic synthesis: Adv. Heterocycl. Chem., 55, 130 (1992).