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Pyridostigmine Bromide_Molecular_structure_CAS_101-26-8)
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Pyridostigmine Bromide

Catalog No. S1608 Name Selleck Chemicals
CAS Number 101-26-8 Website http://www.selleckchem.com
M. F. C9H13BrN2O2 Telephone (877) 796-6397
M. W. 261.11572 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72763

SYNONYMS

IUPAC name
3-[(dimethylcarbamoyl)oxy]-1-methylpyridin-1-ium bromide
IUPAC Traditional name
pyridostigmine bromide
Synonyms
Mestinon
Regonol

DATABASE IDS

CAS Number 101-26-8

PROPERTIES

Salt Data Bromide
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Pyridostigmine Bromide(Mestinon) is a parasympathomimetic and a reversible cholinesterase inhibitor. Pyridostigmine Bromide inhibits acetylcholinesterase in the synaptic cleft, thus slowing down the hydrolysis of acetylcholine. It is a quaternary carbamate inhibitor of cholinesterase that does not cross the blood-brain barrier, and it is taken daily in anticipation of an attack, which carbamylates about 30% of peripheral cholinesterase enzyme. The carbamylated enzyme eventually regenerates by natural hydrolysis and excess ACh levels revert to normal. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Pyridostigmine