Triphenylphosphine, powder

• Catalog No.: L02502
• CAS Number: 603-35-0
• M. F.: C18H15P
• M. W.: 262.285461
• Purity: 99%

SYNONYMS

• Title: 三苯基膦, 粉末
• IUPAC name: triphenylphosphane
• IUPAC Traditional name: triphenylphosphine
• Synonyms: TPP

DATABASE IDS

• Beilstein Number: 610776
• CAS Number: 603-35-0
• Merck Index: 149743
• MDL Number: MFCD00003043
• EC Number: 210-036-0

PROPERTIES

• Purity: 99%
• Boiling Point: 360°C
• Density: 1.200
• Flash Point: 181°C(358°F)
• Melting Point: 79-81°C
• GHS Hazard statements: H302-H317-H413
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P280-P302+P352-P321-P301+P312-P501A
• Risk Statements: 22-43-53
• RTECS: SZ3500000
• Safety Statements: 24-37-61
• TSCA Listed: 是

REFERENCES

• In suitable circumstances, the iminophosphorane may undergo intramolecular aza-Wittig reaction: Tetrahedron, 45, 6375 (1989):
  
• Reviews: Aza-Wittig reaction in heterocyclic synthesis: Org. Prep. Proced. Int., 24, 209 (1992); Iminophosphoranes as building blocks for the preparation of N-containing heterocycles: Synthesis, 1197 (1994).
• For use in the Mitsunobu reaction for conversion of alcohols to alkylating agents, see N-Guanylurea sulfate, A19106, and Diisopropyl azodicarboxylate, L10386. See also 1,2-Bis(diphenylphosphino)ethane, A11419.
• Finds widespread use as a complexing agent with transition metals, either in the preparation of stable complexes, or as an additive in metal-promoted reactions. See also Tri(o-tolyl)phosphine, A12093 and Tri(2-furyl)phosphine, L13329.
• Azides can be converted selectively to amines, in the presence of ester, epoxide or nitro groups, by reduction to iminophosphoranes (Staudinger reaction), followed by hydrolysis. For reviews, see: Tetrahedron, 37, 437 (1981); 48, 1353 (1992):
  
• For use in peptide and other coupling reactions, see 2,2'-Dipyridyl disulfide, A11118.