N-Methylhydroxylamine hydrochloride

• Catalog No.: L02202
• CAS Number: 4229-44-1
• M. F.: CH5ClNO
• M. W.: 82.5095
• Purity: 98%

SYNONYMS

• Title: N-甲基羟基胺盐酸盐
• IUPAC name: hydroxy(methyl)azanium chloride
• IUPAC Traditional name: hydroxy(methyl)azanium chloride

DATABASE IDS

• Beilstein Number: 3541409
• CAS Number: 4229-44-1
• MDL Number: MFCD00012597
• EC Number: 224-181-2

PROPERTIES

• Purity: 98%
• Melting Point: 80-86°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Hygroscopic
• TSCA Listed: 是

REFERENCES

• Reacts with aldehydes and ketones to give nitrones, which undergo 1,3-dipolar addition reactions with alkenes. Cycloaddition to trimethylvinylsilane has been used in a 2-carbon extension of aldehydes to ɑ?-unsaturated aldehydes: J. Org. Chem., 49, 3421 (1984):
  
• Intramolecular cycloaddition has been used as a route to bicyclic systems, e.g. from citronellal: Org. Synth. Coll., 6, 670 (1988).
• Reviews: 1,3-Dipolar cycloadditions of nitrones: Synthesis, 205 (1975). The [3+2] nitrone-olefin cycloaddition reaction: Org. React., 36, 1 (1988). Synthetic applications of nitrones: Org. Prep. Proced. Int., 17, 25 (1985).
• For conversion to, and reactions of, the N,O-bis(TMS) derivative, see: J. Chem. Soc., Perkin 1, 1823 (1989).