N,N-Dimethylacetamide dimethyl acetal

• Catalog No.: L01642
• CAS Number: 18871-66-4
• M. F.: C6H15NO2
• M. W.: 133.1888
• Purity: tech. 90%, stab with 5-10% methanol

SYNONYMS

• Title: N,N-二甲基胺乙酰缩二甲醇
• IUPAC name: (1,1-dimethoxyethyl)dimethylamine
• IUPAC Traditional name: (1,1-dimethoxyethyl)dimethylamine

DATABASE IDS

• EC Number: 242-641-0
• CAS Number: 18871-66-4
• MDL Number: MFCD00008476
• Beilstein Number: 1420865

PROPERTIES

• Purity: tech. 90%, stab with 5-10% methanol
• Boiling Point: 118-120°C
• Density: 0.911
• Flash Point: 8°C(46°F)
• Refractive Index: 1.4120
• GHS Hazard statements: H224-H301-H311-H332-H371
• European Hazard Symbols: X
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P301+P310-P303+P361+P353-P361-P405-P501A
• Risk Statements: 11-20/21/22-68/20/21/22
• Safety Statements: 9-36/37
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 3
• UN Number: UN1993
• Packing Group: II

REFERENCES

• Reacts with 1,2-diols, e.g. sugars, to form 1-(dimethylamino)ethylidene cyclic acetals which can be cleaved with aqueous AcOH, giving the monoacetate of the less hindered OH, thus providing a method for selective monoprotection of the diol: Can. J. Chem., 50, 233 (1972).
• Reacts with active methylene compounds to give the (dimethylamino)ethylidene derivatives: Liebigs Ann. Chem., 641, 1 (1961), compare N,N-Dimethylformamide dimethyl acetal, A15350.
• For use in the N-acetylation of amides to give diacylamines (imides) in high yield, see: Synthesis, 119 (1980).