Methylphosphonic bis(dimethylamide)

• Catalog No.: L00983
• CAS Number: 2511-17-3
• M. F.: C5H15N2OP
• M. W.: 150.159161
• Purity: 97%

SYNONYMS

• Title: 甲基膦酸双(二甲胺)
• IUPAC name: [(dimethylamino)(methyl)phosphoryl]dimethylamine
• IUPAC Traditional name: [dimethylamino(methyl)phosphoryl]dimethylamine
• Synonyms: Pentamethylphosphonic diamide; Methanephosphonic acid bis(dimethylamide)

DATABASE IDS

• CAS Number: 2511-17-3
• Beilstein Number: 1753415
• EC Number: 219-728-7
• MDL Number: MFCD00015433

PROPERTIES

• Purity: 97%
• Boiling Point: 74-75°C/1.5mm
• Density: 1.024
• Flash Point: 108°C(226°F)
• Refractive Index: 1.4590
• GHS Hazard statements: H331-H302-H312
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P280-P302+P352-P321-P405-P501A
• Risk Statements: 20/21/22
• Safety Statements: 36/37
• TSCA Listed: 否
• Hazard Class: 6.1
• UN Number: UN3278
• Packing Group: III

REFERENCES

• Lithiation followed by reaction with a carbonyl compound gives a ?-hydroxyphosphonamide, readily dehydrated to an alkene: J. Am. Chem. Soc., 90, 6816 (1968):
  
• This procedure is complementary to the Horner-Wadsworth-Emmons method (see Appendix 1) since it allows stereochemical control and is especially useful for the synthesis of highly-substituted alkenes. Additional groups can be introduced by alkylation prior to condensation.