2-(2-Bromoethyl)-1,3-dioxane

• Catalog No.: L00958
• CAS Number: 33884-43-4
• M. F.: C6H11BrO2
• M. W.: 195.05434
• Purity: 98%

SYNONYMS

• Title: 2-(2-溴乙基)-1,3-二氧杂环乙烷
• IUPAC name: 2-(2-bromoethyl)-1,3-dioxane
• IUPAC Traditional name: 2-(2-bromoethyl)-1,3-dioxane
• Synonyms: 2-Bromopropionaldehyde trimethylene acetal; 2-Bromopropanal 1,3-propanediol acetal

DATABASE IDS

• MDL Number: MFCD00006567
• EC Number: 251-716-7
• Beilstein Number: 1421628
• CAS Number: 33884-43-4

PROPERTIES

• Purity: 98%
• Boiling Point: 67-70°C/3mm
• Density: 1.434
• Flash Point: 96°C(204°F)
• Refractive Index: 1.4820
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• TSCA Listed: 是

REFERENCES

• Provides a useful means of introducing a masked ?-formylethyl group. In comparison with the corresponding dioxolane (following entry), the dioxane is more stable to acid, and the Grignard is thermally stable. Reaction of the Grignard with an acid chloride gives the ketone in high yield without further reaction to the tertiary alcohol. Subsequent hydrolysis of the 1,3-dioxane gives the -ketoaldehyde: J. Org. Chem., 41, 560 (1976).