Trichloroacetyl isocyanate

• Catalog No.: L00226
• CAS Number: 3019-71-4
• M. F.: C3Cl3NO2
• M. W.: 188.3966
• Purity: 97%

SYNONYMS

• Title: 三氯乙酰基异氰酸酯
• IUPAC name: trichloroethanecarbonyl isocyanate
• IUPAC Traditional name: trichloroethanecarbonyl isocyanate

DATABASE IDS

• EC Number: 221-165-7
• Beilstein Number: 971201
• CAS Number: 3019-71-4
• MDL Number: MFCD00002033

PROPERTIES

• Purity: 97%
• Boiling Point: 58-60°C/20mm
• Density: 1.585
• Flash Point: 65°C(149°F)
• Refractive Index: 1.4800
• GHS Hazard statements: H330-H334-H314-H318-H227
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P210-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501A
• Risk Statements: 14-23-34-42
• Safety Statements: 23-26-30-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN2927
• Packing Group: II

REFERENCES

• [2+2]-Cycloaddition with cyclic enol ethers gives fused azetidinones: Tetrahedron, 45, 227 (1989).
• Causes characteristic chemical shifts in the ɑ-protons of alcohols by in situ conversion to the carbamates: Anal. Chem., 431 (1965).
• Reacts with nucleophiles to give ureas, carbamates, etc., from which the trichloroacetyl group can readily be removed. For reaction of acyl isocyanates with Grignard reagents to give primary carboxamides, see: Tetrahedron Lett., 981 (1975).
• Reviews: Chemistry of ɑ-haloisocyanates: Synthesis, 85 (1980). General isocyanate chemistry: Appendix 3.