p-Toluenesulfonic anhydride

• Catalog No.: L00160
• CAS Number: 4124-41-8
• M. F.: C14H14O5S2
• M. W.: 326.38796
• Purity: 97%

SYNONYMS

• Title: 对甲苯磺酸酐
• IUPAC name: 4-methylbenzenesulfonyl 4-methylbenzene-1-sulfonate
• IUPAC Traditional name: 4-methylbenzenesulfonyl 4-methylbenzenesulfonate
• Synonyms: Tosic anhydride

DATABASE IDS

• EC Number: 223-926-9
• Beilstein Number: 2223702
• MDL Number: MFCD00008548
• CAS Number: 4124-41-8

PROPERTIES

• Purity: 97%
• Melting Point: 125-130°C
• GHS Hazard statements: H314-H318
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 8
• UN Number: UN3261
• Packing Group: III

REFERENCES

• More powerful sulfonylating reagent than the sulfonyl chloride, also avoiding possible displacement of sulfonate by halide. This is particularly useful in the sulfonylation of hindered alcohols and sugars: J. Chem. Soc., 1225 (1953).
• Anions of ?-ketoesters react with p-toluenesulfonic anhydride to give enol tosylates in good yield; tosyl chloride gives poor results (ca 20%): Synth. Commun., 20, 881 (1990).
• Has been used in combination with Paraformaldehyde, A11313 in the generation of monomeric formaldehyde: Synlett, 704 (1990).