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Fesoterodine fumarate

Catalog No. S2240 Name Selleck Chemicals
CAS Number 286930-03-8 Website http://www.selleckchem.com
M. F. C30H41NO7 Telephone (877) 796-6397
M. W. 527.64904 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72721

SYNONYMS

IUPAC name
(2E)-but-2-enedioic acid 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate
IUPAC Traditional name
fesoterodine; fumaric acid
Synonyms
Toviaz

DATABASE IDS

CAS Number 286930-03-8

PROPERTIES

Target mAChRs
Salt Data fumarate
Storage Condition -20°C

DETAILS

Description (English)
Biological Activity:
Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. Fesoterodine fumarate (Toviaz) is used to treat the symptoms of overactive bladder. Fesoterodine fumarate (Toviaz) is unique in that the parent compound has no antimuscarinic efficacy due to its rapid and complete hydrolysis after oral administration. The active metabolite, 5-hydroxymethyl tolterodine, is responsible for all of the antimuscarinic effects. [1][2]

REFERENCES

  • Gomelsky A et al. Drugs Today (Barc). 2010 Feb;46(2):81-90.