Ibuprofen Lysine

• Catalog No.: S1518
• CAS Number: 57469-77-9
• M. F.: C19H32N2O4
• M. W.: 352.46838
• Storage: -20°C

SYNONYMS

• IUPAC name: (2S)-2,6-diaminohexanoic acid; 2-[4-(2-methylpropyl)phenyl]propanoic acid
• IUPAC Traditional name: L-lysine; ibuprofen
• Synonyms: Advil; NeoProfen; Nurofen; Motrin

DATABASE IDS

• CAS Number: 57469-77-9

PROPERTIES

• Target: COX
• Salt Data: Lysine
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Inflammation
Biological Activity:
Ibuprofen Lysine (NeoProfen) is a non-selective COX inhibitor with an IC50 of 0.33 mM. It is known to have an antiplatelet effect, though Ibuprofen Lysine (NeoProfen) is relatively mild and short-lived when compared with that of aspirin or other better-known antiplatelet agents. [1] Ibuprofen, indomethacin, and meclofenamate were potent inhibitors of the microsomal cyclooxygenase prepared from feline lung with IC50 of 0.33 mM, 29 μM, and 4.7 μM, respectively. [2]