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Cidofovir

Catalog No. S1516 Name Selleck Chemicals
CAS Number 113852-37-2 Website http://www.selleckchem.com
M. F. C8H14N3O6P Telephone (877) 796-6397
M. W. 279.187021 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 253

SYNONYMS

IUPAC name
({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
IUPAC Traditional name
cidofovir
Synonyms
Vistide

DATABASE IDS

CAS Number 113852-37-2

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Cidofovir(Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis. (IC50= 0.94 μM) [1][2] A wild type HCMV laboratory strain (AD 169) and 3 ganciclovir-resistant clinical isolates(generated as a result of Ganciclovir therapy) that are cross-resistant to cidofovir were also included in the cidofovir susceptibility assays. AD 169 showed a cidofovir IC50 value of 0.6 pM, and the ganciclovir- resistant isolates showed cidofovir IC50 values ranging from 2.3 to 16 pM. [3]

REFERENCES

  • http://en.wikipedia.org/wiki/Cidofovir