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Polymyxin B sulphate_Molecular_structure_CAS_1405-20-5)
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Polymyxin B sulphate

Catalog No. S1395 Name Selleck Chemicals
CAS Number 1405-20-5 Website http://www.selleckchem.com
M. F. C56H100N16O17S Telephone (877) 796-6397
M. W. 1301.5552 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72659

SYNONYMS

IUPAC name
N-[3-amino-1-({1-[(3-amino-1-{[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)carbamoyl]-2-hydroxypropyl}carbamoyl)propyl]-6-methyloctanamide; sulfuric acid
IUPAC Traditional name
N-[3-amino-1-({1-[(3-amino-1-{[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)carbamoyl]-2-hydroxypropyl}carbamoyl)propyl]-6-methyloctanamide; sulfuric acid
Synonyms
Poly-RX
Aerosporin
PMB

DATABASE IDS

CAS Number 1405-20-5

PROPERTIES

Salt Data sulphate
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Polymyxin B is an antibiotic primarily used for resistant gram-negative infections. Polymyxins bind to the cell membrane and alter its structure making it more permeable. The resulting water uptake leads to cell death. They are cationic, basic proteins that act like detergents (surfactants). It is commonly used in the topical first-aid preparation Neosporin. [1]

REFERENCES

  • http://www.rxlist.com/polymyxin-b-drug.htm