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Ondansetron hydrochloride_Molecular_structure_CAS_99614-01-4)
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Ondansetron hydrochloride

Catalog No. S1390 Name Selleck Chemicals
CAS Number 99614-01-4 Website http://www.selleckchem.com
M. F. C18H20ClN3O Telephone (877) 796-6397
M. W. 329.8239 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72655

SYNONYMS

IUPAC name
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one hydrochloride
IUPAC Traditional name
ondansetron hydrochloride
Synonyms
Emetron
Ondemet
Emeset
Zofran

DATABASE IDS

CAS Number 99614-01-4

PROPERTIES

Target 5-HT receptor
Salt Data Hydrochloride
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting, often following chemotherapy. Its effects are thought to be on both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Ondansetron