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Acitretin

Catalog No. S1368 Name Selleck Chemicals
CAS Number 55079-83-9 Website http://www.selleckchem.com
M. F. C21H26O3 Telephone (877) 796-6397
M. W. 326.42934 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72641

SYNONYMS

IUPAC name
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
IUPAC Traditional name
acitretin
Synonyms
Soriatane

DATABASE IDS

CAS Number 55079-83-9

PROPERTIES

Salt Data Free Base
Solubility DMSO
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Inflammation
Biological Activity:
Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin’s half-life is approximately 2 days. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Acitretin