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Chelerythrine Chloride

Catalog No. S1292 Name Selleck Chemicals
CAS Number 3895-92-9 Website http://www.selleckchem.com
M. F. C21H18ClNO4 Telephone (877) 796-6397
M. W. 383.82492 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72613

SYNONYMS

IUPAC name
17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2,4(8),9,11,14,16,18,20-nonaen-21-ium chloride
IUPAC Traditional name
chelerythrine chloride

DATABASE IDS

CAS Number 3895-92-9

PROPERTIES

Target PKC
Salt Data Chloride
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Inflammation
Biological Activity:
Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable PKC inhibitor (IC50 = 660 nM). It has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. [1,2]References on Chelerythrine Chloride[1] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, November 15, 1990 , 172:993-999

REFERENCES

  • http://en.wikipedia.org/wiki/Chelerythrine