1,1'-(Azodicarbonyl)dipiperidine

• Catalog No.: H27719
• CAS Number: 10465-81-3
• M. F.: C12H20N4O2
• M. W.: 252.3128
• Purity: 97%

SYNONYMS

• Title: 1,1'-(偶氮二羰基)二哌啶
• IUPAC name: (NE)-N-{[(E)-piperidine-1-carbonyl]imino}piperidine-1-carboxamide
• IUPAC Traditional name: (NE)-N-[(E)-piperidine-1-carbonylimino]piperidine-1-carboxamide
• Synonyms: ADDP

DATABASE IDS

• MDL Number: MFCD00010111
• CAS Number: 10465-81-3

PROPERTIES

• Purity: 97%
• Melting Point: 133-136°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• TSCA Listed: 否

REFERENCES

• Reagent for the Mitsunobu reaction (see Diethyl azodicarboxylate, L19348), used in combination with tri-n-butylphosphine as a more powerful system than DEAD for higher pK_a nucleophiles: Tetrahedon Lett., 34, 1639 (1993); Tetrahedron, 61, 6218 (2005). Has also been utilized in a selective method for converting primary and secondary alcohols to carbonyl compounds, by reaction of the alcohol with a Grignard reagent, followed by oxidation of the intermediate magnesio-derivative with ADDP: J. Org. Chem., 38, 1652 (1973); Bull. Chem. Soc. Jpn., 2773 (1977).