Tetra-n-propylammonium perruthenate(VII)

• Catalog No.: B24511
• CAS Number: 114615-82-6
• M. F.: C12H28NO4Ru
• M. W.: 351.42502
• Purity: 98%

SYNONYMS

• Title: 四正丙基过钌(VII)酸铵
• IUPAC name: tetrapropylazanium rutheniumoylolate
• IUPAC Traditional name: tetrapropylammonium rutheniumoylolate
• Synonyms: TPAP

DATABASE IDS

• CAS Number: 114615-82-6
• MDL Number: MFCD00074914

PROPERTIES

• Purity: 98%
• Melting Point: 160°C dec.
• GHS Hazard statements: H272-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• European Hazard Symbols: Oxidising (O)
• GHS Precautionary statements: P221-P210-P305+P351+P338-P302+P352-P405-P501A
• Risk Statements: 5-8-36/37/38
• Safety Statements: 17-26-37
• Storage Warning: Hygroscopic
• TSCA Listed: 否
• Hazard Class: 5.1
• UN Number: UN1479
• Packing Group: III

REFERENCES

• For a brief feature on uses in synthesis, see: Synlett, 824 (2007).
• Selective, catalytic oxidant introduced by Ley. Normally used in combination with N-methylmorpholine-N-oxide as the stoichiometric reoxidant and 4A molecular sieves to remove water. Preferred solvents are dichloromethane and acetonitrile. Primary and secondary alcohols are oxidized to aldehydes and ketones in high yield: J. Chem. Soc., Chem. Commun., 1625 (1987). For an example of alcohol to aldehyde oxidation in the partial synthesis of the acyl tetronic acid ionophore tetronasin, see: Tetrahedron Lett., 35, 319 (1994). Also useful for a number of other oxidations such as lactols to lactones and sulfides to sulfones. For oxidation of secondary amines to imines, and of hydroxylamines to nitrones, see: Tetrahedron Lett., 35, 6567, 6571 (1994).
• For a comprehensive review of this reagent, see: Synthesis, 639 (1994). For a review of ruthenium oxo-complexes as organic oxidants, see: Chem. Soc. Rev., 21, 179 (1992).