Ethyl (methylthio)acetate

• Catalog No.: B24285
• CAS Number: 4455-13-4
• M. F.: C5H10O2S
• M. W.: 134.1967
• Purity: 98%

SYNONYMS

• Title: 甲硫基乙酸乙酯
• IUPAC name: ethyl 2-(methylsulfanyl)acetate
• IUPAC Traditional name: ethyl 2-(methylsulfanyl)acetate
• Synonyms: (Methylthio)acetic acid ethyl ester

DATABASE IDS

• Beilstein Number: 1744999
• MDL Number: MFCD00009182
• CAS Number: 4455-13-4
• EC Number: 224-700-2

PROPERTIES

• Purity: 98%
• Boiling Point: 176°C
• Density: 1.06
• Flash Point: 59°C(138°F)
• Refractive Index: 1.4600
• GHS Hazard statements: H226-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 36/37
• Safety Statements: 26
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 3
• UN Number: UN3272
• Packing Group: III

REFERENCES

• In the presence of chlorine or t-butyl hypochlorite, substituted anilines give ortho-substituted derivatives via a base-promoted Sommelet-Hauser type rearrangement of an intermediate azasulfonium salt: J. Am. Chem. Soc., 96, 5512 (1974):
  
• The products are used in the synthesis of oxindoles; see, e.g.: J. Heterocycl. Chem., 28, 1525 (1991).
• Under photochemical conditions, alkenes are converted to the homologated saturated ethyl esters: Tetrahedron Lett., 38, 7829 (1997).