N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

• Catalog No.: B23760
• CAS Number: 77377-52-7
• M. F.: C9H18F3NOSi
• M. W.: 241.3260296
• Purity: 97%

SYNONYMS

• Title: N-(叔丁基二甲基硅烷)-N-三氟乙酰胺
• IUPAC name: N-(tert-butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide
• IUPAC Traditional name: N-(tert-butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide
• Synonyms: MTBSTFA; TBSTFA

DATABASE IDS

• MDL Number: MFCD00009671
• EC Number: 000-000-0
• CAS Number: 77377-52-7
• Beilstein Number: 3606546

PROPERTIES

• Purity: 97%
• Boiling Point: 168-170°C
• Density: 1.023
• Flash Point: 52°C(125°F)
• Refractive Index: 1.4020
• GHS Hazard statements: H226-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-36/37/38
• Safety Statements: 7-26-33-37-60
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 3
• UN Number: UN1993
• Packing Group: III

REFERENCES

• Reactive silylating agent effective in acetonitrile for introduction of the TBDMS group with alcohols, thiols, amines, amides, carboxylic acids, as well as conversion of enolizable carbonyl groups to silyl enol ethers: J. Org. Chem., 47, 3336 (1982). See Appendix 4.