Trimethylacetic anhydride

• Catalog No.: B22983
• CAS Number: 1538-75-6
• M. F.: C10H18O3
• M. W.: 186.24812
• Purity: 99%

SYNONYMS

• Title: 三甲基乙酸酐
• IUPAC name: 2,2-dimethylpropanoyl 2,2-dimethylpropanoate
• IUPAC Traditional name: trimethylacetic anhydride
• Synonyms: Pivalic anhydride

DATABASE IDS

• CAS Number: 1538-75-6
• Beilstein Number: 386552
• EC Number: 216-263-1
• MDL Number: MFCD00008842

PROPERTIES

• Purity: 99%
• Boiling Point: 193°C
• Density: 0.918
• Flash Point: 63°C(145°F)
• Refractive Index: 1.4090
• GHS Hazard statements: H314-H318-H227
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P280-P305+P351+P338-P309-P310
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN3265
• Packing Group: III

REFERENCES

• The direct hydrogenation of carboxylic acids to aldehydes has been achieved in the presence of pivalic anhydride and Tetrakis(triphenylphosphine)palladium(0), 10548: Chem. Lett., 1143 (1998).
• Alcohols can be protected as their pivaloyl (Pv) esters by reaction with the anhydride in the presence of MgBr₂ - Et₃N or Sc(OTf)₃ in acetonitrile: J. Org. Chem., 61, 5702 (1996). See also Trimethylacetyl chloride, A15051.