Methoxylamine hydrochloride

• Catalog No.: A19188
• CAS Number: 593-56-6
• M. F.: CH6ClNO
• M. W.: 83.51744
• Purity: 98+%

SYNONYMS

• Title: 甲氧胺盐酸盐
• IUPAC name: O-methylhydroxylamine hydrochloride
• IUPAC Traditional name: O-methylhydroxylamine hydrochloride
• Synonyms: O-METHYLHYDROXYLAMINE HYDROCHLORIDE; Methoxylamine hydrochloride

DATABASE IDS

• Beilstein Number: 3589723
• EC Number: 209-798-7
• Merck Index: 145989
• CAS Number: 593-56-6
• MDL Number: MFCD00012951

PROPERTIES

• Purity: 98+%
• Melting Point: ca 148°C dec.
• GHS Hazard statements: H301-H317-H314-H318-H400
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 22-34-43-50
• RTECS: NC3980000
• Safety Statements: 26-36/37/39-45-61
• Storage Warning: Hygroscopic
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN3261
• Packing Group: III

REFERENCES

• In the presence of KO-t-Bu and a copper catalyst in DMF, aminates nitroarenes at the ortho (predominantly) and para positions: J. Org. Chem., 61, 442 (1996).
• Reacts with aldehydes and ketones to give O-methyloximes: J. Org. Chem., 27, 914 (1962); 28, 1523 (1963); Anal. Biochem., 22, 284 (1968). Open-chain aldoses have been prepared by ozonolysis of the methoximes of fully-acylated sugars: J. Org. Chem., 54, 4957 (1989).
• As with oximes, the lithiation of methoximes results in abstraction of a proton syn to the oxygen function (coordination stabilization): J. Org. Chem., 41, 439 (1976). For a review of the alkylation of carbonyl compounds via their nitrogen-containing derivatives, see: Synthesis, 517 (1983).