Dimethylthexylchlorosilane

• Catalog No.: A19140
• CAS Number: 67373-56-2
• M. F.: C8H19ClSi
• M. W.: 178.77496
• Purity: 95%

SYNONYMS

• Title: 二甲基叔己基氯化硅
• IUPAC name: chloro(2,3-dimethylbutan-2-yl)dimethylsilane
• IUPAC Traditional name: chloro(2,3-dimethylbutan-2-yl)dimethylsilane
• Synonyms: Chlorodimethylthexylsilane; Dimethyl(2,3-dimethylbutyl)chlorosilane

DATABASE IDS

• Beilstein Number: 3647960
• CAS Number: 67373-56-2
• MDL Number: MFCD00012175

PROPERTIES

• Purity: 95%
• Boiling Point: 55-56°C/10mm
• Density: 0.911
• Flash Point: 51°C(124°F)
• Melting Point: 14-15°C
• Refractive Index: 1.4500
• GHS Hazard statements: H314-H318-H226
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-34
• Safety Statements: 23-26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 8
• UN Number: UN2986
• Packing Group: II

REFERENCES

• Reagent for the introduction, in the presence of a base such as triethylamine or imidazole in DMF, of the thexyldimethylsilyl (TDS) group for protection of hydroxyl functions. The greater steric hindrance of the TDS group compared with TBDMS confers greater (at least 2-3x) stability to acid or base hydrolysis. Cleavage with F^- is also about 2-3x slower than for TBDMS: Tetrahedron Lett., 26, 5511 (1985); 32, 2135 (1991). TDS is also an extremely useful protecting group for nitrogen functions, providing readily purifiable derivatives which survive a variety of chemical transformations, but are readily cleaved by F^-: Tetrahedron Lett., 26, 5515 (1985); J. Chem. Soc., Perkin 1, 423 (1998).