2-Bromopropionic acid

• Catalog No.: A17569
• CAS Number: 598-72-1
• M. F.: C3H5BrO2
• M. W.: 152.9746
• Purity: 98%

SYNONYMS

• Title: 2-溴丙酸
• IUPAC name: 2-bromopropanoic acid
• IUPAC Traditional name: α-bromopropionic acid

DATABASE IDS

• CAS Number: 598-72-1
• MDL Number: MFCD00004211
• EC Number: 209-947-6
• Beilstein Number: 605451

PROPERTIES

• Purity: 98%
• Boiling Point: 202-203°C
• Density: 1.700
• Flash Point: 100°C(212°F)
• Melting Point: 25°C
• Refractive Index: 1.4750
• GHS Hazard statements: H301-H314-H318
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 22-34
• RTECS: UA2451715
• Safety Statements: 20-26-36/37/39-45
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN3261
• Packing Group: II

REFERENCES

• For a simplified variant of the reaction, applicable to the synthesis of ɑ-unsubstituted cinnamic acids, see Chloroacetic acid, A11482.
• Reaction of ɑ-halo alkanoic acids with a dialkyl phosphite in the presence of NaH, followed by treatment of the resulting phosphonoacetate salt with an aldehyde (or cycloalkanone) provides a convenient one-pot alternative to the Knoevenagel or Horner-Wadsworth-Emmons reactions for the synthesis of a variety of substituted acrylic acids: J. Org. Chem., 46, 2514 (1981):