Trichloromethyl chloroformate

• Catalog No.: A17444
• CAS Number: 503-38-8
• M. F.: C2Cl4O2
• M. W.: 197.8322
• Purity: 98%

SYNONYMS

• Title: 氯甲酸三氯甲酯
• IUPAC name: trichloromethyl chloroformate
• IUPAC Traditional name: trichloromethyl chloroformate
• Synonyms: Chloroformic acid trichloromethyl ester; Diphosgene

DATABASE IDS

• CAS Number: 503-38-8
• EC Number: 207-965-9
• Beilstein Number: 970225
• Merck Index: 143334
• MDL Number: MFCD00015553

PROPERTIES

• Purity: 98%
• Boiling Point: 128°C
• Density: 1.640
• Flash Point: >110°C(230°F)
• Melting Point: -57°C
• Refractive Index: 1.4570
• GHS Hazard statements: H330-H314-H318
• European Hazard Symbols: Highly toxic (T+)
• GHS Precautionary statements: P280-P303+P361+P353-P305+P351+P338-P304+P340-P310
• Risk Statements: 26-34
• RTECS: LQ7350000
• Safety Statements: 26-27/28-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN3390
• Packing Group: I

REFERENCES

• Convenient replacement for phosgene in many reactions, for example:
• Conversion of amines to isocyanates: J. Org. Chem., 41, 2070 (1976); Org. Synth. Coll ., 6, 715 (1988). For aliphatic amines, best results were obtained in the presence of the hindered amine 1,8-Bis(dimethylamino)naphthalene, L00313: J. Org. Chem., 61, 3883 (1996).
• Dehydration of N-monosubstituted formamides to isocyanides: Angew. Chem. Int. Ed., 16, 259 (1977).
• Formation of nitriles from oximes Synthesis, 1037 (1986); or carboxamides: Tetrahedron Lett., 27, 2203 (1986).
• See also Triphosgene, A14932, and Oxalyl chloride, A18012.