Zinc chloride, anhydrous

• Catalog No.: A16281
• CAS Number: 7646-85-7
• M. F.: Cl2Zn
• M. W.: 136.286
• Purity: 98+%

SYNONYMS

• Title: 无水氯化锌
• IUPAC name: zinc(2+) ion dichloride
• IUPAC Traditional name: zinc(2+) ion dichloride

DATABASE IDS

• MDL Number: MFCD00011295
• Merck Index: 1410132
• EC Number: 231-592-0
• CAS Number: 7646-85-7

PROPERTIES

• Purity: 98+%
• Boiling Point: 732°C
• Density: 2.91
• Melting Point: 290°C
• GHS Hazard statements: H314-H400-H410-H302
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• Risk Statements: 22-34-50/53
• RTECS: ZH1400000
• Safety Statements: 1/2-26-36/37/39-45-60-61
• Storage Warning: Hygroscopic
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN2331
• Packing Group: III

REFERENCES

• Reacts with NaBH₄ in ether or THF to give zinc borohydride; Zn(BH₄)₂, which is used in situ as a versatile, non-basic, selective reducing agent. Review: Synlett, 885 (1993). The reactivity of Zn(BH₄)₂ has the advantage of being relatively non-toxic. See, e.g.: Selective reduction of aldehydes in the presence of ketones: Tetrahedron Lett., 31, 7663 (1990). Reduction of aliphatic esters to alcohols: Indian J. Chem B, 31B, 701 (1992). Reduction of indoles to indolines: Heterocycles, 26, 1771 (1987). In combination with trifluoroacetic anhydride for the selective reduction of acids to alcohols: J. Chem. Soc., Perkin 1, 1561 (1992). The same reduction has also been performed by Zn(BH₄)₂ alone in refluxing THF: J. Org. Chem., 60, 5314 (1995). In combination with paraformaldehyde, for reductive alkylation of amines: J. Chem. Soc., Perkin 1, 1 (1994).
• Mild Lewis acid catalyst in a wide variety of reactions.
• Catalyst for the Hoesch reaction for the acylation of reactive aromatics with nitriles. For an example, see: Org. Synth. Coll., 2, 522 (1943).
• Effective catalyst for the Knoevenagel condensation; see: Tetrahedron Lett., 32, 5821 (1991).
• Milder catalyst than Titanium(IV) chloride, 14713, for the ɑ-tert-alkylation of sensitive silyl enol ethers: Chem. Ber., 113, 3734 (1980).