4-Methylmorpholine N-oxide monohydrate

• Catalog No.: A15996
• CAS Number: 70187-32-5
• M. F.: C5H13NO3
• M. W.: 135.16162
• Purity: 98+%

SYNONYMS

• Title: 4-甲基吗啉-N-氧化物单水合物
• IUPAC name: 4-methylmorpholin-4-ium-4-olate hydrate
• IUPAC Traditional name: N-methylmorpholine N-oxide hydrate
• Synonyms: N-Methylmorpholine N-oxide monohydrate; NMMO

DATABASE IDS

• CAS Number: 70187-32-5
• Beilstein Number: 5449441
• EC Number: 231-391-8
• MDL Number: MFCD00149388

PROPERTIES

• Purity: 98+%
• Melting Point: 73-76°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Hygroscopic
• TSCA Listed: 是

REFERENCES

• In the presence of Ru catalysts such as RuCl₃ or Dichlorotris(triphenylphosphine)ruthenium(II), L00373, oxidizes various types of alcohol to carbonyl compounds: Tetrahedron Lett., 2503 (1976). See also Tetra-n-propylammonium perruthenate(VII), B24511.
• Boronic esters formed by treatment of aryl bromides in THF with n-BuLi, followed by trimethyl borate, can be oxidized in situ to phenols without isolation of the boronic acid: Synlett, 931 (1995).
• In the presence of 4A molecular sieves in acetonitrile, activated (e.g. benzylic) halides can be oxidized to aldehydes and ketones: Synth. Commun., 22, 1967 (1992).
• Stoichiometric oxidant permitting the use of Osmium(VIII) oxide, 12103, catalytically in the cis-hydroxylation of alkenes: Tetrahedron Lett., 1973 (1976): Org. Synth. Coll., 6, 342 (1988). For use in the asymmetric dihydroxylation (ADH) reaction, catalyzed by Osmium(VIII) oxide, 12103, see: J. Am. Chem. Soc., 110, 1968 (1988); Org. Synth. Coll., 9, 383 (1998).