tert-Butyl chloroacetate

• Catalog No.: A15833
• CAS Number: 107-59-5
• M. F.: C6H11ClO2
• M. W.: 150.60334
• Purity: 98%

SYNONYMS

• Title: 氯乙酸叔丁酯
• IUPAC name: tert-butyl 2-chloroacetate
• IUPAC Traditional name: tert-butyl 2-chloroacetate
• Synonyms: Chloroacetic acid tert-butyl ester

DATABASE IDS

• Beilstein Number: 1753006
• MDL Number: MFCD00000930
• EC Number: 203-506-1
• Merck Index: 141563
• CAS Number: 107-59-5

PROPERTIES

• Purity: 98%
• Boiling Point: 155°C
• Density: 1.053
• Flash Point: 46°C(115°F)
• Refractive Index: 1.4230
• GHS Hazard statements: H331-H302-H312-H315-H319-H335-H226-H400-H410
• European Hazard Symbols: X
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P280H-P273-P305+P351+P338-P309-P310-P501A
• Risk Statements: 10-20/21/22-36/37/38-50/53
• RTECS: AF8985500
• Safety Statements: 26-36/37-45-60-61
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN2929
• Packing Group: II

REFERENCES

• The reaction with imines has also been used in the preparation of aziridines by a nitrogen analogue of the Darzens reaction: J. Chem. Soc., Chem. Commun., 602 (1977).
• Darzens condensation (see Ethyl chloroacetate, A15554) with carbonyl compounds gives t-butyl glycidic esters, which readily undergo decarboxylative elimination to the homologous aldehydes. See, for example: Rec. Trav. Chim.,89, 18 (1970).