(±)-Epichlorohydrin

• Catalog No.: A15823
• CAS Number: 106-89-8
• M. F.: C3H5ClO
• M. W.: 92.5242
• Purity: 99%

SYNONYMS

• Title: (+/-)-环氧氯丙烷
• IUPAC name: 2-(chloromethyl)oxirane
• IUPAC Traditional name: epichlorohydrin
• Synonyms: (±)-1-Chloro-2,3-epoxypropane

DATABASE IDS

• EC Number: 203-439-8
• Merck Index: 143611
• MDL Number: MFCD00005132
• CAS Number: 106-89-8
• Beilstein Number: 79785

PROPERTIES

• Purity: 99%
• Boiling Point: 115-117°C
• Density: 1.182
• Flash Point: 32°C(90°F)
• Melting Point: -57°C
• Refractive Index: 1.4380
• GHS Hazard statements: H301-H311-H331-H317-H350-H314-H226
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P210-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
• Risk Statements: 45-10-23/24/25-34-43
• RTECS: TX4900000
• Safety Statements: 53-45
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN2023
• Packing Group: II

REFERENCES

• The preparation of glycidyl ethers, often carried out in two steps, via the ring-opened chlorohydrin ether and subsequent ring-closure with base, can be achieved as a single step, under phase-transfer conditions: Synthesis, 117 (1983). For extension to diglycidyl ethers of diols, see: Synthesis, 649 (1985).
• For use as an acid scavenger in bromination reactions, see: J. Am. Chem. Soc., 95, 4419 (1973).
• Reaction with primary amines provides a one-step route to 3-azetidinols: J. Org. Chem., 55, 2920 (1990):