4-Nitrobenzyl chloride

• Catalog No.: A15749
• CAS Number: 100-14-1
• M. F.: C7H6ClNO2
• M. W.: 171.58104
• Purity: 99%

SYNONYMS

• Title: 4-硝基苄氯
• IUPAC name: 1-(chloromethyl)-4-nitrobenzene
• IUPAC Traditional name: 1-(chloromethyl)-4-nitrobenzene
• Synonyms: alpha-Chloro-4-nitrotoluene

DATABASE IDS

• Beilstein Number: 387187
• CAS Number: 100-14-1
• EC Number: 202-822-7
• MDL Number: MFCD00007374

PROPERTIES

• Purity: 99%
• Melting Point: 70-74°C
• GHS Hazard statements: H301-H332-H314-H318-H341
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 20/22-34-68
• RTECS: XS9093000
• Safety Statements: 26-36/37/39-45
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN3261
• Packing Group: II

REFERENCES

• Reagent for carboxyl protection in peptide synthesis. Derivatives are stable to HBr, but cleaved by hydrogenolysis: J. Am. Chem. Soc., 81, 5691 (1959); J. Chem. Soc., 4922 (1965). See also 4-Nitrobenzyl alcohol, A15742, 4-Nitrobenzyl bromide, A15236, and Appendix 6.
• Has also been used for protection of the thiol group: J. Org. Chem., 37, 3550 (1972); J. Chem. Soc., Chem. Commun., 12 (1974).