Ethyl 4-chloroacetoacetate

• Catalog No.: A15641
• CAS Number: 638-07-3
• M. F.: C6H9ClO3
• M. W.: 164.58686
• Purity: 97%

SYNONYMS

• Title: 4-氯乙酰乙酸乙酯
• IUPAC name: ethyl 4-chloro-3-oxobutanoate
• IUPAC Traditional name: ethyl 4-chloro-3-oxobutanoate
• Synonyms: 4-Chloroacetoacetic acid ethyl ester

DATABASE IDS

• MDL Number: MFCD00000939
• EC Number: 211-317-0
• Beilstein Number: 1761275
• CAS Number: 638-07-3

PROPERTIES

• Purity: 97%
• Boiling Point: 220°C
• Density: 1.212
• Flash Point: 92°C(198°F)
• Melting Point: -8°C
• Refractive Index: 1.4520
• GHS Hazard statements: H301-H314-H318-H227-H401-H411
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P210-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 25-34-51/53
• RTECS: AK5110000
• Safety Statements: 26-36/37/39-45-57
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN2922
• Packing Group: II

REFERENCES

• Isothiocyanates similarly give 2-aminothiophenones: J. Chem. Soc., Perkin 1, 1078 (1981).
• Reacts at the 2-position with isocyanates in the presence of base to give 2-aminofuranone derivatives via a ketene N-acetal intermediate: Chem. Ber., 109, 212 (1976):
  
• Acid-catalyzed reaction with phenols gives 3-(chloromethyl)coumarins, readily convertible to benzofuran-3-acetic acids: Heterocycles, 41, 647 (1995):