Chlorotriethylsilane

• Catalog No.: A15547
• CAS Number: 994-30-9
• M. F.: C6H15ClSi
• M. W.: 150.7218
• Purity: 98+%

SYNONYMS

• Title: 三乙基氯硅烷
• IUPAC name: chlorotriethylsilane
• IUPAC Traditional name: chlorotriethylsilane
• Synonyms: TESCl; Triethylchlorosilane

DATABASE IDS

• Beilstein Number: 1732860
• MDL Number: MFCD00000507
• EC Number: 213-615-6
• CAS Number: 994-30-9

PROPERTIES

• Purity: 98+%
• Boiling Point: 145-147°C
• Density: 0.899
• Flash Point: 29°C(84°F)
• Melting Point: ca -75°C
• Refractive Index: 1.4310
• GHS Hazard statements: H301-H314-H318-H226
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P280-P305+P351+P338-P309-P310-P403
• Risk Statements: 10-14-22-35
• Safety Statements: 26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN2986
• Packing Group: II

REFERENCES

• Silylation reagent (see Appendix 4). Generally, triethylsilyl (TES) ethers are 10-100x more stable to hydrolysis than their TMS (see Chlorotrimethylsilane, A13651) counterparts but much less so than TBDMS (see tert-Butyldimethylchlorosilane, A13064): J. Org. Chem., 48, 1970 (1983).
• Silylation of alcohols in the presence of e.g. pyridine: J. Chem. Soc., Chem. Commun., 156 (1979); imidazole-DMF: Helv. Chim. Acta, 64, 2002 (1981); or catalyzed by DMAP: J. Org. Chem., 52, 598 (1987) have been reported. The TES group is readily cleaved with TBAF or other F^- reagents. Catalytic amounts of FeCl₃ in MeOH has also been recommended: Synlett, 1260 (2006). Selective cleavage in the presence of TBDMS has been achieved with aqueous AcOH in THF: Liebigs Ann. Chem., 1281 (1986), or 2% HF in acetonirile: Tetrahedron Lett., 26, 5239 (1985).