Ethyl diphenylphosphinite

• Catalog No.: A15087
• CAS Number: 719-80-2
• M. F.: C14H15OP
• M. W.: 230.242061
• Purity: 98%

SYNONYMS

• Title: 二苯基次磷酸乙酯
• IUPAC name: ethyl diphenylphosphinite
• IUPAC Traditional name: ethyl diphenylphosphinite
• Synonyms: Diphenylphosphinous acid ethyl ester; Ethoxydiphenylphosphine

DATABASE IDS

• Beilstein Number: 1641750
• MDL Number: MFCD00009087
• EC Number: 211-951-8
• CAS Number: 719-80-2

PROPERTIES

• Purity: 98%
• Boiling Point: 179-180°C/14mm
• Density: 1.064
• Flash Point: >110°C(230°F)
• Refractive Index: 1.5900
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Air & Moisture Sensitive
• TSCA Listed: 否

REFERENCES

• Arbuzov reaction with alkyl halides gives diphenyl phosphine oxides, useful as Wittig-Horner intermediates. See, for example: Synthesis, 126 (1977); Tetrahedron Lett., 2433 (1979); Appendix 1.
• An iminophosphorane, formed with an azido ester (Staudinger), reacts with a carboxyl group to form an amide, providing the basis of a novel peptide coupling method. The reaction occurs at lower temperatures with this reagent rather than tributyl- or triphenylphosphine: J. Org. Chem., 50, 2601 (1985). See Appendix 6.