2-(Trifluoromethyl)aniline

• Catalog No.: A15072
• CAS Number: 88-17-5
• M. F.: C7H6F3N
• M. W.: 161.1244496
• Purity: 98%

SYNONYMS

• Title: 2-(三氟甲基)苯胺
• IUPAC name: 2-(trifluoromethyl)aniline
• IUPAC Traditional name: 2-(trifluoromethyl)aniline
• Synonyms: 2-Aminobenzotrifluoride

DATABASE IDS

• Beilstein Number: 879494
• MDL Number: MFCD00007718
• CAS Number: 88-17-5
• EC Number: 201-806-7

PROPERTIES

• Purity: 98%
• Boiling Point: 67-68°C/15mm
• Density: 1.295
• Flash Point: 65°C(149°F)
• Melting Point: -35 to -33°C
• Refractive Index: 1.4800
• GHS Hazard statements: H318-H315-H373-H302-H335-H227-H401-H411
• European Hazard Symbols: X
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P280-P273-P305+P351+P338-P337+P313
• Risk Statements: 22-33-37/38-41-51/53
• Safety Statements: 26-36/37/39-61
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN2942
• Packing Group: III

REFERENCES

• The CF₃ group promotes ionization of the amino group under basic conditions which also make the CF₃ unusually reactive towards nucleophiles. Many examples have been reported by L. Strekowski et al in which various heterocyclic systems have been synthesized. See, e.g.: J. Org. Chem., 59, 5886 (1994); Tetrahedron Lett., 35,7597 (1994) and refs therein: