Trimethylacetaldehyde

• Catalog No.: A15013
• CAS Number: 630-19-3
• M. F.: C5H10O
• M. W.: 86.1323
• Purity: 96%

SYNONYMS

• Title: 三甲基乙醛
• IUPAC name: 2,2-dimethylpropanal
• IUPAC Traditional name: pivalaldehyde
• Synonyms: Pivaldehyde

DATABASE IDS

• Beilstein Number: 506060
• EC Number: 211-134-6
• MDL Number: MFCD00006962
• CAS Number: 630-19-3

PROPERTIES

• Purity: 96%
• Boiling Point: 74-76°C
• Density: 0.775
• Flash Point: -15°C(5°F)
• Melting Point: 6°C
• Refractive Index: 1.3794
• GHS Hazard statements: H225
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P243-P403
• Risk Statements: 11
• Safety Statements: 9-16-33
• Storage Warning: Air Sensitive
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1989
• Packing Group: II

REFERENCES

• Promotes the epoxidation of alkenes with molecular oxygen: Tetrahedron Lett., 33, 6827 (1992).
• Derivatizing agent for amino acids, forming oxazolidinones as volatile derivatives for GC: Anal. Biochem., 49, 442 (1972); Aust. J. Biol. Sci., 26, 831 (1973).
• For formation of the fused pyrrolidino-oxazolidinone from L-proline, catalyzed by trifluoroacetic acid, and use of the product in a synthesis of ɑ-branched amino acids, see: Org. Synth.Coll., 9, 626 (1998):
  
• For use in the protection of asparagine as a tetrahydropyrimidinone derivative, see: Org. Synth.Coll., 9, 17 (1998). For use of this system in ɑ-alkylation of (S)-asparagine with self-regeneration of the stereogenic center, see: J. Org. Chem., 63, 4706 (1998).
• The imine formed with ethylamine has been used to convert aryl chlorides to the hindered tertiary amides: N-ethyl-N-(1-methoxy-2,2-dimethylpropyl)benzamides, which can be ortho metallated cleanly at higher temperatures than other amide systems: J. Org. Chem., 60, 8417 (1995).