1-Bromo-3,3,3-trifluoroacetone

• Catalog No.: A14948
• CAS Number: 431-35-6
• M. F.: C3H2BrF3O
• M. W.: 190.9465896
• Purity: 97%

SYNONYMS

• Title: 1-溴-3,3
• IUPAC name: 3-bromo-1,1,1-trifluoropropan-2-one
• IUPAC Traditional name: 3-bromo-1,1,1-trifluoropropan-2-one
• Synonyms: 1-Bromo-3,3,3-trifluoro-2-propanone; 3-Bromo-1,1,1-trifluoroacetone

DATABASE IDS

• CAS Number: 431-35-6
• EC Number: 207-071-9
• MDL Number: MFCD00039237
• Beilstein Number: 1703387

PROPERTIES

• Purity: 97%
• Boiling Point: 85-87°C
• Density: 1.822
• Flash Point: -2°C(28°F)
• Melting Point: <-80°C
• Refractive Index: 1.3760
• GHS Hazard statements: H225-H314-H318
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 11-34
• Safety Statements: 9-16-26-36/37/39-45
• TSCA Listed: 否
• Hazard Class: 3
• UN Number: UN2924
• Packing Group: II

REFERENCES

• A novel reductive olefination reaction with aldehydes, mediated by Ti(O-i-Pr)₄ and PPh₃, provides a one-pot synthesis of trifluoromethylated trans-allylic alcohols: Chem. Commun., 2195 (1998):
  
• The oxime is readily converted with base to the highly reactive species 1,1,1-trifluoro-2-nitroso-2-propene, which undergoes hetero-Diels-Alder reactions, e.g. with cyclopentadiene or indole to give fused oxazolines. The indole adduct rearomatizes to give 1-(3-indolyl)-3,3,3-trifluoroacetoxime: J. Org. Chem., 57, 339 (1992).