2,3,5-Trimethylpyrazine

• Catalog No.: A14870
• CAS Number: 14667-55-1
• M. F.: C7H10N2
• M. W.: 122.1677
• Purity: 99%

SYNONYMS

• Title: 2,3,5-三甲基吡嗪
• IUPAC name: 2,3,5-trimethylpyrazine
• IUPAC Traditional name: pyrazine, trimethyl-

DATABASE IDS

• Beilstein Number: 2423
• CAS Number: 14667-55-1
• EC Number: 238-712-0
• MDL Number: MFCD00006145

PROPERTIES

• Purity: 99%
• Boiling Point: 171-172°C
• Density: 0.979
• Flash Point: 54°C(129°F)
• Refractive Index: 1.5050
• GHS Hazard statements: H226-H302-H315-H319-H335
• European Hazard Symbols: X
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-22-36/37/38
• RTECS: UQ3907000
• Safety Statements: 26-36/37
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1993
• Packing Group: III

REFERENCES

• Lithiation leads to products of metallation at the 3- and 2-methyl groups in that order, whereas attack at the 5-methyl, surprisingly, is disfavored. For a detailed study of lithiation with LDA, see: J. Org. Chem., 48, 2130 (1983). For subsequent reaction with trans-1,2-dichloroethylene to give isomeric pyrrolo[1,2-a]pyrazines, see: J. Heterocycl. Chem., 18, 445 (1981).