(Methoxymethyl)triphenylphosphonium chloride

• Catalog No.: A14380
• CAS Number: 4009-98-7
• M. F.: C20H20ClOP
• M. W.: 342.798961
• Purity: 98+%

SYNONYMS

• Title: (甲氧基甲基)三苯基氯化磷鎓
• IUPAC name: (methoxymethyl)triphenylphosphanium chloride
• IUPAC Traditional name: (methoxymethyl)triphenylphosphanium chloride

DATABASE IDS

• EC Number: 223-664-5
• Beilstein Number: 924215
• MDL Number: MFCD00011800
• CAS Number: 4009-98-7

PROPERTIES

• Purity: 98+%
• Melting Point: ca 190°C dec.
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P301+P310-P305+P351+P338-P302+P352-P405-P501A
• Risk Statements: 22-36/37/38
• Safety Statements: 26-36/37
• Storage Warning: Hygroscopic
• TSCA Listed: 否

REFERENCES

• Wittig reaction (see Appendix 1) of the derived phosphorane with aldehydes and ketones gives enol ethers, readily hydrolyzed to homologous aldehydes. For an example (adamantanone to adamantanecarboxaldehyde), see: Chem. Ber., 95, 2514 (1962). For use of the reaction in the synthesis of hydroisoquinoline AMPA antagonists, see: J. Med. Chem., 39, 2219 (1996). Reaction with chiral 2,3-epoxyaldehydes provides an enantioselective synthesis of (E)-4-hydroxyalkenes: J. Chem. Soc., Chem. Commun., 232 (1993).