4-Nitrophenol

• Catalog No.: A14376
• CAS Number: 100-02-7
• M. F.: C6H5NO3
• M. W.: 139.1088
• Purity: 99%

SYNONYMS

• Title: 4-硝基苯酚
• IUPAC name: 4-nitrophenol
• IUPAC Traditional name: p-nitrofenol

DATABASE IDS

• EC Number: 202-811-7
• Beilstein Number: 1281877
• MDL Number: MFCD00007331
• Merck Index: 146621
• CAS Number: 100-02-7

PROPERTIES

• Purity: 99%
• Boiling Point: 279°C dec.
• Density: 1.480
• Flash Point: 169°C(336°F)
• Melting Point: 110-115°C
• Solubility: Freely soluble in alcohol, chloroform, ether
• GHS Hazard statements: H373-H302-H312-H332
• European Hazard Symbols: X
• GHS Precautionary statements: P260-P261-P280-P302+P352-P304+P340-P501A
• Risk Statements: 20/21/22-33
• RTECS: SM2275000
• Safety Statements: 28
• Storage Warning: Light Sensitive
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN1663
• Packing Group: III

REFERENCES

• Acid-base indicator: pH 5.6 - 7.6.
• Forms active esters with N-protected amino acids, useful in peptide synthesis; see, for example: J. Org. Chem., 62, 1356 (1997). For peptide reagents, see Appendix 6.
• Suzuki-type coupling of the triflate with various arylboronic acids gives biaryl derivatives: Tetrahedron, 45, 6679 (1984). For an example of Stille coupling of the triflate with an arylstannane, catalyzed by trans-Dichlorobis(triphenylphosphine)palladium(II), 10491, see: Org. Synth. Coll., 9, 553 (1998).