Tetramethyldisilazane

• Catalog No.: A14304
• CAS Number: 15933-59-2
• M. F.: C4H15NSi2
• M. W.: 133.3396
• Purity: 98+%

SYNONYMS

• Title: 四甲基二硅氮烷
• IUPAC name: bis(dimethylsilyl)amine
• IUPAC Traditional name: bis(dimethylsilyl)amine

DATABASE IDS

• Beilstein Number: 741869
• EC Number: 240-072-2
• CAS Number: 15933-59-2
• MDL Number: MFCD00025626

PROPERTIES

• Purity: 98+%
• Boiling Point: 99-100°C
• Density: 0.768
• Flash Point: -3°C(26°F)
• Refractive Index: 1.4055
• GHS Hazard statements: H225-H314-H318
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P280-P303+P361+P353-P305+P351+P338-P310
• Risk Statements: 11-34
• Safety Statements: 16-26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN2924
• Packing Group: II

REFERENCES

• Reagent for the preparation (see Appendix 4) of dimethylsilyl (DMS) derivatives, compare Hexamethyldisilazane, A15139. With allylic and homoallylic alcohols, the products can undergo Pt- or Rh-catalyzed intramolecular hydrosilylation, providing a regioselective route to 1,3-diols: J. Am. Chem. Soc., 108, 6090 (1986). For an example of this reaction, see Chlorodimethylsilane, A13113.
• The potassium derivative, formed by reaction with KH in THF, reacts with alkyl halides to give, after hydrolysis, high yields of primary amines, thus providing a convenient alternative to the classical Gabriel method. Other silazanes, including hexamethyldisilazane, give lower yields: Synthesis, 150 (1995):