1,1-Cyclobutanedicarboxylic acid

• Catalog No.: A14288
• CAS Number: 5445-51-2
• M. F.: C6H8O4
• M. W.: 144.12532
• Purity: 99%

SYNONYMS

• Title: 1,1-环丁烷二羧酸
• IUPAC name: cyclobutane-1,1-dicarboxylic acid
• IUPAC Traditional name: H2cbdca

DATABASE IDS

• MDL Number: MFCD00001325
• EC Number: 226-651-2
• Beilstein Number: 2046031
• CAS Number: 5445-51-2

PROPERTIES

• Purity: 99%
• Melting Point: ca 158°C dec.
• GHS Hazard statements: H314-H318
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN3261
• Packing Group: III

REFERENCES

• Metal chelating agent giving complexes some of which have importance as antitumour agents. Study of diamine-platinum complexes: Investigational New Drugs, 9, 1, (1991). See also feature article on platinum antitumor chemistry: Chem. Commun., 801 (1996).
• Used in preparation of technetium complexes for brain tomography: USP 4,895,960 (1991).
• Reaction with sulfuryl chloride under free-radical conditions gives 3-chlorocyclobutanecarboxylic acid: Org. Synth. Coll., 6, 271 (1988); the product has been used in the synthesis of a nucleoside antiviral agent: Tetrahedron Lett., 30, 6955 (1989).