3-Ethoxy-2-cyclohexen-1-one

• Catalog No.: A14224
• CAS Number: 5323-87-5
• M. F.: C8H12O2
• M. W.: 140.17968
• Purity: 99%

SYNONYMS

• Title: 3-乙氧基-2-环己烯-1-酮
• IUPAC name: 3-ethoxycyclohex-2-en-1-one
• IUPAC Traditional name: 3-ethoxycyclohex-2-en-1-one

DATABASE IDS

• CAS Number: 5323-87-5
• EC Number: 226-190-7
• MDL Number: MFCD00001580
• Beilstein Number: 2042049

PROPERTIES

• Purity: 99%
• Boiling Point: 76-78°C/1mm
• Density: 1.04
• Flash Point: 107°C(224°F)
• Refractive Index: 1.5060
• TSCA Listed: 否

REFERENCES

• Useful intermediate for the preparation of 3-alkyl- or aryl-2-cyclohexen-1-ones, by addition of organometallic reagents and subsequent hydrolysis: J. Am. Chem. Soc., 70, 2174 (1948); 72, 1645 (1950); Helv. Chim. Acta, 36, 482 (1963). For an example of this transformation in the total synthesis of axane sesquiterpenoids, see: J. Org. Chem., 61, 473 (1996):
  
• Under conditions of kinetic enolate formation (LDA), alkylation occurs at the 6-position: the Stork-Danheiser kinetic alkylation procedure, which has found extensive use in alicyclic synthesis: J. Org. Chem., 38, 1775 (1973); Org. Synth. Coll., 7, 208 (1990) and references therein.