Tetraisopropyl methylenediphosphonate

• Catalog No.: A13484
• CAS Number: 1660-95-3
• M. F.: C13H30O6P2
• M. W.: 344.321222
• Purity: 98%

SYNONYMS

• Title: 亚甲基二磷酸四异丙酯
• IUPAC name: bis(propan-2-yl) {[bis(propan-2-yloxy)phosphoryl]methyl}phosphonate
• IUPAC Traditional name: diisopropyl (diisopropoxyphosphoryl)methylphosphonate
• Synonyms: Methylenediphosphonic acid tetraisopropyl ester; Methylenephosphonic acid tetraisopropyl ester

DATABASE IDS

• EC Number: 216-765-0
• MDL Number: MFCD00015021
• CAS Number: 1660-95-3
• Beilstein Number: 1080180

PROPERTIES

• Purity: 98%
• Boiling Point: 122-124°C/1.5mm
• Density: 1.080
• Flash Point: 160°C(320°F)
• Refractive Index: 1.4340
• GHS Hazard statements: H318
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280-P305+P351+P338-P310
• Risk Statements: 41
• Safety Statements: 26-39-60
• TSCA Listed: 是

REFERENCES

• Horner-Wadsworth-Emmons olefination (see Appendix 1) with carbonyl compounds yields vinylphosphonates: Synth. Commun., 10, 299 (1980). A synthesis of allenes via a double HWE olefination has been described: Tetrahedron, 58, 83 (2002):
  
• gem-Bisphosphonates have application in bone tissue therapy: Synthesis, 661 (1991).